Most of the victims were five or six years old. Three days of mourning have been declared and classes at the school have been suspended.
The cause of the fire is not clear. There is a need for more school buildings in Niger so extra classrooms are made of wood and straw.
This fire comes after at least 20 children died in a similar fire in April.
According to Reuters, the council of ministers said that following the two incidents, preschool classes must not be held in straw-roof huts.
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